Photo:Morsa Images/Getty Images Almost two-thirds of U.S. states failed to prioritize cancer patients for COVID-19 vaccinations despite recommendations from the Centers for Disease Control and Prevention, according to a study presented this week at the annual meeting of the Radiological Society of North America. Cancer patients are particularly vulnerable to the […]
Breast Cancer
Black women are more likely to develop lymphe
SAN ANTONIO – Black women experienced higher rates of breast cancer-related lymphedema than white women, and Black race was the strongest predictor of lymphedema development, according to results presented at the San Antonio Breast Cancer Symposium, held December 7-10, 2021. Lymphedema is a well-known side effect of breast cancer […]
ctDNA Promising Biomarker in Ribociclib, Letrozole-Treated HR+/HER2- Advanced Breast Cancer
The presence of detectable mutation in a baseline liquid biopsy appeared to be a negative prognostic factor for women with hormone receptor-positive (HR+)/HER2-negative (HER2-) advanced breast cancer treated with first-line ribociclib and letrozole, according to the results of the BioItaLEE trial (ClinicalTrials.gov Identifier: NCT03439046). The absence of a target mutation […]
Some Treatment Outcomes Do Not Differ Between Black and White Patients With Breast Cancer, But Disparities Persist
Patient race did not significantly impact the percentage of patients who had no detectable disease in biopsied/surgically removed tissue after treatment (known as pathologic complete response) or event-free survival in patients with high-risk breast cancer who received presurgical chemotherapy. However, disparities existed for a subgroup of women who did not […]
Biotechs Share Promising Breast Cancer Data at San Antonio Symposium
The 2021 San Antonio Breast Cancer Symposium (SABCS) is meeting December 7–10 at the Henry B. Gonzalez Convention Center in San Antonio, Texas, and virtually. Here’s a look at some of the top presentations so far. Intensity’s Intratumoral Therapy Shows Promise in Early Breast Cancer Study Intensity Therapeutics, based in […]
Trastuzumab ADC Active in HER2-Low, HER2-Undetected Breast Cancer
SAN ANTONIO — A headline-making antibody-drug conjugate (ADC) continued to impress breast cancer specialists by demonstrating activity in tumors with low HER2 expression and in some breast cancers with undetectable HER2. As expected, trastuzumab deruxtecan (T-DXd, Enhertu) showed robust activity in HER2-overexpressing metastatic breast cancer, producing objective responses in 71% […]
Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients
Summary Background Previous studies have independently validated the prognostic relevance of residual cancer burden (RCB) after neoadjuvant chemotherapy. We used results from several independent cohorts in a pooled patient-level analysis to evaluate the relationship of RCB with long-term prognosis across different phenotypic subtypes of breast cancer, to assess generalisability in […]
Patient Race Doesn’t Significantly Impact Pathological CR After Neoadjuvant Therapy for Breast Cancer
Although significant disparities for a subgroup of women who did not achieve a pathologic complete response (pCR) were observed, patient race did not significantly impact pCR and event-free survival (EFS) in patients with high-risk breast cancer who received targeted neoadjuvant chemotherapy, according to results presented by Beverly Kyalwazi, BS, at […]
How I Feel About My Breasts Now That I’ve Had Breast Cancer Treatment
I’m grateful for my boobs. I love them. Even and especially after feeding three babies with them—one after cancer! I kind of always hated them before. They weren’t the right size or shape; never made me feel like I was enough. When I was diagnosed, so many people had the […]
Newly linked genomic and pathologic features provide a singular biological framework — ScienceDaily
Researchers at UNC Lineberger Comprehensive Cancer Center have taken a major step forward in melding two key methods for studying breast cancer: one by genetic analysis and the second by looking at the architecture of cells, or their pathology. The investigators were able to link the two thanks to a […]