Furthermore, previous analysis of the SWOG-8814 trial (NCT00929591) showed that post-menopausal women with LN involvement and an RS of 31 or more who were given chemotherapy plus tamoxifen had a survival benefit over those receiving tamoxifen alone.5 Therefore, we recommend adjuvant chemotherapy in addition to adjuvant endocrine therapy in this […]
Breast Cancer
Antibody-Drug Conjugates May Represent the Future of HER2-Low Breast Cancer Treatment
Emerging data with novel antibody-drug conjugates (ADCs) such as trastuzumab deruxtecan-nxki (Enhertu), vic-trastuzumab duocarmazine, and disitamab vedotin (Aidixi) are showing encouraging activity in HER2-low breast cancer. Paolo Tarantino, MD, said this data suggests that the classification of HER2 should go beyond merely positive or negative. “In the future, we will […]
Adjuvant Everolimus Fails to Stop Recurrence in Early High-Risk Breast Cancer
Adding mTOR inhibitor everolimus (Afinitor) to adjuvant endocrine therapy failed to improve disease-free survival (DFS) in high-risk hormone receptor-positive/HER2-negative (HR+/HER2-), a large randomized trial showed. Three-year DFS was 88% with everolimus plus endocrine therapy and 89% with placebo plus endocrine therapy. Tolerability figured prominently in the results, as more than […]
Patient voices a good predictor of cancer treatment outcomes — ScienceDaily
A breast cancer patient’s perspective on their physical well-being can provide a better indication of their response to cancer treatment than clinician-based tools, a new study has found, highlighting the importance of shared decision-making in the treatment process. The research also identified differences between clinician-based data and the patient-reported data, […]
Expression of Sex Hormones in Oral Squamous Cell Carcinoma: A Systematic Review on Immunohistochemical Studies
Oral squamous cell carcinoma (OSCC) is the most commonly occurring cancer in the head and neck region, with an estimate of 6,50,000 new cases worldwide every year [1]. The mortality rate of oral cancer is high, with 4,50,000 deaths per year. Several etiological factors, such as smoking and alcohol consumption, […]
Agendia Achieves Historic Milestone of Enrolling 10,000 Patients in FLEX, the Largest-Ever Prospective, Real-World-Evidence Trial for Patients With Early Stage Breast Cancer
IRVINE, Calif. & AMSTERDAM–(BUSINESS WIRE)–Agendia, Inc., a commercial-stage company focused on improving outcomes for breast cancer patients worldwide by providing physicians and patients with next-generation diagnostic and information solutions to inform optimized treatment decision-making, today announced 10,000 patients have been successfully enrolled in the FLEX Registry. Agendia’s unique FLEX Registry […]
Susan G. Komen Awards Grant to Define and Advance Diagnosis of Inflammatory Breast Cancer
Newswise — Susan G. Komen®, the world’s leading breast cancer organization, awarded a research grant to apply a new, first-of-its-kind tool that seeks to more accurately diagnose inflammatory breast cancer (IBC). The grant funds collaborative work being done at two of the largest IBC centers in the world – The […]
ESR1 Mutations Provide Window Into Breast Cancer Metastasis
Present in approximately two-thirds of estrogen receptor-positive breast cancers, the role of ESR1 mutations in disease metastasis is poorly defined. Present in approximately two-thirds of estrogen receptor (ER)-positive breast cancers, the role of ESR1 mutations in disease metastasis is poorly defined.1 “It is an important research area because it is […]
Kerry O’Riordan McAdam, inspirational breast-cancer fund-raiser, business professional, and fitness enthusiast, has died at 31
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Kerry O’Riordan McAdam, 31, of Philadelphia’s Fairmount neighborhood, a dynamic and inspirational fund-raiser for the fight against breast cancer, business professional, and lifelong fitness enthusiast, died Tuesday, April 26, of metastatic breast cancer at home. Ms. McAdam was diagnosed with metastatic breast cancer, also known as stage IV, in February […]
Global Breast Cancer Treatment Drugs Market Report, Growth Insight, Deep Research & Segment Analysis
Global “Breast Cancer Treatment Drugs Market” Reports 2022 provide key industry studies for Breast Cancer Treatment Drugs manufacturers with specific statistics, significance, definition, SWOT analysis, expert opinion and the latest developments in the world. The research report also covers market size, price, sales, revenue, market shares, gross margin, growth rate […]
Evidence for Practice and Research Recommendations
This review article written by Danielle Gentile, PhD, et al, reviews the management of cancer-related fatigue in integrative oncology. ABSTRACT Cancer-related fatigue (CRF) is one of the most common symptoms across the cancer continuum and is often underreported and undertreated. Defined as a distressing, persistent, subjective sense of tiredness or […]
Danielle Wiggins and Regina Brett discuss breast cancer and exams
Danielle Wiggins met up with writer Regina Brett at The Gathering Place to talk about how to turn a difficult experience into a gift that helps others. BEACHWOOD, Ohio — We are launching a new initiative here at 3News that we’re calling “Do it for Danielle” in the hopes of […]