In this study, we investigated pRNFL thickness, peripapillary VD, and their ratio in T2DM patients without clinical DR to understand the relationship between DRN and microvascular impairment in more detail, and found that pRNFL thickness and VD were significantly reduced in the DM group, and the RNFL/VD ratio was significantly […]
Diabetes
Concerning Trends in Vision Impairment for Adults With Diabetes?
Declines in vision impairment among people with diabetes appear to have plateaued, according to 20-year CDC data, and there’s now even a hint of an increase in more recent years. Over the two-decade period from 1999 to 2019, there was a slight change in the prevalence of adults with diabetes […]
Diabetes Tied to Faster Progression to Overt Heart Failure
Diabetes, especially when uncontrolled, is strongly associated with progression to overt heart failure in patients with preclinical signs of heart failure, a new study shows. “Until now, studies of diabetes and heart failure have mainly been done in patients with overt heart failure. The novelty of this study is that […]
Type 1 and Type 2
Diabetes impacts your body’s ability to control your blood sugar (glucose) levels. Uncontrolled blood sugar can lead to serious complications, which is why monitoring your blood sugar and keeping it within recommended ranges is so important. Your recommended blood sugar range can be impacted by a variety of factors such […]
Using Personal Fat Thresholds to Reach Type 2 Diabetes Remission
Body mass index (BMI) may not play as significant a role in defining type 2 diabetes risk or remission status as previously thought. A new late-breaking study presented at the American Diabetes Association (ADA) 2022 Scientific Session this week showed that the mechanistic changes behind type 2 diabetes remission among […]
Peripheral Arterial Disease Prevalence with Diabetes
Introduction Neuropathy prevalence in people with diabetes1 and the annual diabetes-related lower extremity amputation rate2 are high in Barbados. Diabetic foot disease accounts for 89% of diabetes-related admissions to the island’s main hospital.3 Peripheral arterial disease (PAD) is a major risk factor for lower extremity amputation in people with diabetes […]
Effect of active vitamin D treatment on development of type 2 diabetes: DPVD randomised controlled trial in Japanese population
Abstract Objective To assess whether eldecalcitol, an active vitamin D analogue2, can reduce the development of type 2 diabetes among adults with impaired glucose tolerance. Design Double blinded, multicentre, randomised, placebo controlled trial. Setting Three hospitals in Japan, between June 2013 and August 2019. Participants People aged 30 years and […]
Arterial Stiffness May Be Superior to Hypertension in Predicting Diabetes
Findings of this study showed arterial stiffness is associated with a higher risk of diabetes onset compared with hypertension. Results of a prospective cohort study, published in Hypertension, revealed that in addition to being associated with hypertension, diabetes is also linked with arterial stiffness (AS); among participants, AS was superior […]
Researchers investigate gestational diabetes mellitus and its association with maternal and fetal outcomes
Gestational diabetes mellitus (GDM) is a chronic condition and the most common health complication associated with pregnancy, thus affecting several million women globally. The number of pregnant women who are diagnosed with GDM is increasing and is believed to be associated with the rising global incidence of obesity. In a […]
Experts Endorse Plant-Based Diet for Type 2 Diabetes Remission
Many adults can achieve remission of type 2 diabetes with a primary intervention consisting of a diet that emphasizes whole, plant-based foods, according to a new publication from the American College of Lifestyle Medicine (ACLM). The document was developed to assist clinicians treating adults with type 2 diabetes, with the […]
Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes
Generation, genetics, and immunological phenotypes of B6 RIP-DTR mice RIP-DTR mouse strains were initially generated and maintained on mixed B6/CBA genetic backgrounds for studies of beta cell regeneration7,10,11. To make an inbred strain of RIP-DTR mice for transplantation studies, we repeatedly backcrossed to B6.SJL-Ptprca Pepcb/BoyJ mice, commonly referred to as […]
Gestational diabetes mellitus and adverse pregnancy outcomes: systematic review and meta-analysis
Abstract Objective To investigate the association between gestational diabetes mellitus and adverse outcomes of pregnancy after adjustment for at least minimal confounding factors. Design Systematic review and meta-analysis. Data sources Web of Science, PubMed, Medline, and Cochrane Database of Systematic Reviews, from 1 January 1990 to 1 November 2021. Review […]