Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK

Anubha Mahajan, Grace Z. Yu, Neil R. Robertson, Nigel W. Rayner, Anna L. Gloyn & Mark I. McCarthy

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK

Anubha Mahajan, Hidetoshi Kitajima, Grace Z. Yu, Sanghoon Moon, Soo-Heon Kwak, Neil R. Robertson, Nigel W. Rayner, Meng Sun, Fernando Abaitua, Adebowale Adeyemo, Cecilia M. Lindgren, Wing Yee So, Konstantin Strauch, Jason M. Torres, Simon R. Myers, Anna L. Gloyn, Mark I. McCarthy & Andrew P. Morris

Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Cassandra N. Spracklen, Laura M. Raffield, Qing Duan, Yun Li & Karen L. Mohlke

Department of Epidemiology and Biostatistics, University of Massachusetts Amherst, Amherst, MA, USA

Cassandra N. Spracklen

Department of Epidemiology and Biostatistics, Imperial College London, London, UK

Weihua Zhang, Marie Loh, Abbas Dehghan & John C. Chambers

Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, London, UK

Weihua Zhang, Jaspal S. Kooner & John C. Chambers

Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA

Maggie C. Y. Ng, Lauren E. Petty & Jennifer E. Below

Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA

Maggie C. Y. Ng, Latchezar Dimitrov, Jacob M. Keaton & Donald W. Bowden

Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA

Maggie C. Y. Ng & Donald W. Bowden

The Advanced Research Center for Innovations in Next-Generation Medicine (INGEM), Tohoku University, Sendai, Japan

Hidetoshi Kitajima

Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan

Hidetoshi Kitajima

Cancer Center, Tohoku University Hospital, Tohoku University, Sendai, Japan

Hidetoshi Kitajima

Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Sina Rüeger, Pietro della Briotta Parolo & Leif Groop

Genetics Institute, University College London, London, UK

Leo Speidel, Sina Rüeger & Pietro della Briotta Parolo

Francis Crick Institute, London, UK

Leo Speidel

Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Republic of Korea

Young Jin Kim, Sanghoon Moon, Bong-Jo Kim, Sohee Han, Mi Yeong Hwang, Hye-Mi Jang, Dong Mun Shin, Kyungheon Yoon & Juyoung Lee

Laboratory for Genomics of Diabetes and Metabolism, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

Momoko Horikoshi, Jack Flanagan, Ken Suzuki & Shiro Maeda

Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA

Josep M. Mercader, Miriam S. Udler, Jose C. Florez & James B. Meigs

Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA

Josep M. Mercader, Varinderpal Kaur, Aaron Leong, Miriam S. Udler & Jose C. Florez

Harvard Medical School, Boston, MA, USA

Josep M. Mercader, Brian E. Cade & Susan Redline

Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA

Daniel Taliun, Ellen M. Schmidt, Christian Fuchsberger, Goncalo Abecasis & Michael Boehnke

Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea

Soo-Heon Kwak & Kyong-Soo Park

Department of Human Genetics, Wellcome Sanger Institute, Hinxton, UK

Nigel W. Rayner, Bram Peter Prins, Sophie Hackinger & Eleftheria Zeggini

Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Nigel W. Rayner & Eleftheria Zeggini

Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore

Marie Loh & John C. Chambers

Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR) and National University of Singapore (NUS), Singapore, Singapore

Marie Loh

Biomedical Sciences Graduate Studies Program, University of California San Diego, La Jolla, CA, USA

Joshua Chiou

Regulatory Genomics and Diabetes, Centre for Genomic Regulation, the Barcelona Institute of Science and Technology, Barcelona, Spain

Irene Miguel-Escalada & Jorge Ferrer

Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Madrid, Spain

Irene Miguel-Escalada & Jorge Ferrer

Nuffield Department of Population Health, University of Oxford, Oxford, UK

Kuang Lin, Fiona Bragg, Zhengming Chen, Iona Y. Millwood & Robin G. Walters

Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK

Fiona Bragg, Zhengming Chen, Iona Y. Millwood & Robin G. Walters

The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Michael H. Preuss, Girish N. Nadkarni, Claudia Schurmann, Erwin P. Bottinger & Ruth J. F. Loos

Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan

Fumihiko Takeuchi, Masato Isono & Norihiro Kato

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands

Jana Nano, Oscar H. Franco, Mohammad Arfan Ikram, Symen Ligthart & Abbas Dehghan

The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, the Lundquist Institute for Biomedical Innovation (formerly Los Angeles Biomedical Research Institute) at Harbor–UCLA Medical Center, Torrance, CA, USA

Xiuqing Guo, Jie Yao, Yang Hai, Jingyi Tan, Kathryn Roll, Kevin Sandow, Kent D. Taylor, Yii-Der Ida Chen & Jerome I. Rotter

Department of Medicine, McMaster University, Hamilton, Ontario, Canada

Amel Lamri, Sonia S. Anand, Hertzel C. Gerstein & Salim Yusuf

Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada

Amel Lamri, Sonia S. Anand, Hertzel C. Gerstein, Salim Yusuf & Guillaume Paré

Public Health Informatics Unit, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan

Masahiro Nakatochi

MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK

Robert A. Scott, Jian’an Luan, Eleanor Wheeler, Claudia Langenberg & Nicholas J. Wareham

Division of Translational Medicine and Human Genetics, University of Pennsylvania, Philadelphia, PA, USA

Jung-Jin Lee & Danish Saleheen

Consejo Nacional de Ciencia y Tecnología (CONACYT), Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

Alicia Huerta-Chagoya

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Mariaelisa Graff, Rebecca Rohde, Eric A. Whitsel & Kari E. North

Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore

Jin-Fang Chai, Victor J. Y. Lim, Rob M. van Dam, E-Shyong Tai & Xueling Sim

Department of Anthropology, University of Toronto at Mississauga, Mississauga, Ontario, Canada

Esteban J. Parra

Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA

Lawrence F. Bielak, Jennifer A. Smith, Patricia A. Peyser & Sharon L. R. Kardia

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan

Yasuharu Tabara, Takahisa Kawaguchi & Fumihiko Matsuda

deCODE Genetics, Amgen Inc., Reykjavik, Iceland

Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Unnur Thorsteinsdottir & Kari Stefansson

Department of Health Data Science, University of Liverpool, Liverpool, UK

James P. Cook, Jack Flanagan & Andrew P. Morris

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

Mart Kals, Krista Fischer, Kristi Läll, Andres Metspalu, Reedik Mägi & Andrew P. Morris

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Niels Grarup, Jette Bork-Jensen, Ruth J. F. Loos, Torben Hansen & Oluf Pedersen

Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA

Ian Pan, Mengna Huang & Simin Liu

Department of Biostatistics, Harvard University, Boston, MA, USA

Tamar Sofer

Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, USA

Tamar Sofer, Brian E. Cade & Susan Redline

Department of Medicine, Harvard University, Boston, MA, USA

Tamar Sofer

Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany

Matthias Wuttke & Anna Köttgen

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA

Chloe Sarnowski, Ching-Ti Liu & Josée Dupuis

German Center for Diabetes Research (DZD), Neuherberg, Germany

Christian Gieger, Christian Herder, Jennifer Kriebel, Annette Peters, Michael Roden, Barbara Thorand & Harald Grallert

Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Christian Gieger, Jennifer Kriebel, Annette Peters, Barbara Thorand & Harald Grallert

Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Christian Gieger, Jennifer Kriebel & Harald Grallert

Department of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA

Darryl Nousome, Roberta McKean-Cowdin & Christopher A. Haiman

Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands

Stella Trompet & J. Wouter Jukema

Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands

Stella Trompet & Raymond Noordam

Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA

Jirong Long, Edmond K. Kabagambe, Jacob M. Keaton, Wei Zheng & Xiao-Ou Shu

Institute for Population and Precision Health, the University of Chicago, Chicago, IL, USA

Lin Tong, Farzana Jasmine, Muhammad G. Kibriya, Mohammad Shahriar & Habibul Ahsan

Department of Public Health Sciences and Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA

Wei-Min Chen, Uma Nayak & Michèle M. Sale

Genomic Research on Complex Diseases (GRC-Group), CSIR–Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India

Meraj Ahmad, K. Radha Mani, Suraj S. Nongmaithem & Giriraj R. Chandak

Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Hong Kong, China

Claudia H. T. Tam, Juliana C. N. Chan, Guozhi Jiang, Andrea O. Luk, Wing Yee So, Brian Tomlinson & Ronald C. W. Ma

Chinese University of Hong Kong–Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, the Chinese University of Hong Kong, Hong Kong, China

Claudia H. T. Tam, Juliana C. N. Chan, Guozhi Jiang, Andrea O. Luk, Yoonjung Yoonie Joo, M. Geoffrey Hayes & Ronald C. W. Ma

Division of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

Yoonjung Yoonie Joo, Yoonjung Yoonie Joo & M. Geoffrey Hayes

Department of Health and Biomedical Informatics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

Yoonjung Yoonie Joo

Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

Chien-Hsiun Chen, Li-Ching Chang, Yuan-Tsong Chen & Jer-Yuarn Wu

Inserm U1283, CNRS UMR 8199, European Genomic Institute for Diabetes, Institut Pasteur de Lille, Lille, France

Cécile Lecoeur, Mickaël Canouil & Philippe Froguel

University of Lille, Lille University Hospital, Lille, France

Cécile Lecoeur, Mickaël Canouil & Philippe Froguel

Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA

Aude Nicolas & Michael A. Nalls

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Lisa R. Yanek & Diane M. Becker

Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA

Guanjie Chen, Adebowale Adeyemo, Ayo P. Doumatey, Daniel Shriner & Charles N. Rotimi

Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA

Richard A. Jensen, Jennifer A. Brody, James S. Floyd & Bruce M. Psaty

Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA

Salman Tajuddin, Michele K. Evans & Alan B. Zonderman

Division of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA

Ping An & Michael A. Province

Department of Research and Evaluation, Division of Biostatistics Research, Kaiser Permanente of Southern California, Pasadena, CA, USA

Anny H. Xiang

Department of Biomedical Science, Hallym University, Chuncheon, South Korea

Hyeok Sun Choi & Yoon Shin Cho

Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Linda S. Adair, Shufa Du & Penny Gordon-Larsen

Unidad de Investigación en Enfermedades Metabólicas and Departamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

Carlos A. Aguilar-Salinas

Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

Masato Akiyama, Yoichiro Kamatani, Ken Suzuki & Atsushi Takahashi

Department of Ocular Pathology and Imaging Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

Masato Akiyama

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada

Sonia S. Anand, Hertzel C. Gerstein & Salim Yusuf

Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA

Alain Bertoni & Yongmei Liu

Chinese Academy of Medical Sciences, Beijing, China

Zheng Bian & Yu Guo

Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark

Ivan Brandslund

Department of Clinical Biochemistry, Vejle Hospital, Vejle, Denmark

Ivan Brandslund

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, USA

Chad M. Brummett

Department of Medicine, Division of Endocrinology and Diabetes, Keck School of Medicine of USC, Los Angeles, CA, USA

Thomas A. Buchanan

Hong Kong Institute of Diabetes and Obesity, the Chinese University of Hong Kong, Hong Kong, China

Juliana C. N. Chan, Wing Yee So & Ronald C. W. Ma

Li Ka Shing Institute of Health Sciences, the Chinese University of Hong Kong, Hong Kong, China

Juliana C. N. Chan & Ronald C. W. Ma

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore

Miao-Li Chee, Charumathi Sabanayagam, Liang Zhang, Tien-Yin Wong & Ching-Yu Cheng

Wellcome Sanger Institute, Hinxton, UK

Ji Chen

Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA

Shyh-Huei Chen

Division of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

Lee-Ming Chuang

Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan

Lee-Ming Chuang

Department of Medicine, University of Vermont, Colchester, VT, USA

Mary Cushman

Section on Endocrinology and Metabolism, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA

Swapan K. Das

Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka

H. Janaka de Silva

Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece

George Dedoussis

Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Shufa Du, Penny Gordon-Larsen & Annie-Green Howard

Department of Nephrology and Medical Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany

Kai-Uwe Eckardt

Department of Nephrology and Hypertension, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

Kai-Uwe Eckardt

Department of Biostatistics, University of Washington, Seattle, WA, USA

Leslie S. Emery, Tin Louie & Adrienne M. Stilp

California Pacific Medical Center Research Institute, San Francisco, CA, USA

Daniel S. Evans

Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK

Ian Ford

Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA

Myriam Fornage

Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK

Timothy M. Frayling

Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA

Barry I. Freedman

Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, Italy

Christian Fuchsberger

Department of Medicine, Division of Endocrinology and Metabolism, Lundquist Research Institute at Harbor–UCLA Medical Center, Torrance, CA, USA

Pauline Genter & Eli Ipp

Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden

Vilmantas Giedraitis & Martin Ingelsson

Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica, Mexico City, Mexico

Clicerio González-Villalpando & Maria Elena González-Villalpando

Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, USA

Mark O. Goodarzi

Center for Epigenomics, University of California San Diego, La Jolla, CA, USA

David Gorkin & Sebastian Preissl

Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA

Myron Gross

University of Exeter Medical School, University of Exeter, Exeter, UK

Andrew T. Hattersley

Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Christian Herder & Michael Roden

Department of Endocrinology and Diabetology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Christian Herder & Michael Roden

Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Annie-Green Howard

Department of Internal Medicine, Diabetes and Metabolism Research Center, the Ohio State University Wexner Medical Center, Columbus, OH, USA

Willa Hsueh

Center for Global Cardiometabolic Health, Brown University, Providence, RI, USA

Mengna Huang & Simin Liu

Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai (CHGC) and Shanghai Institute for Biomedical and Pharmaceutical Technologies (SIBPT), Shanghai, China

Wei Huang & Jinxiu Shi

Division of Endocrine and Metabolism, Tri-Service General Hospital Songshan Branch, Taipei, Taiwan

Yi-Jen Hung

School of Medicine, National Defense Medical Center, Taipei, Taiwan

Yi-Jen Hung & Wayne H. H. Sheu

Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

Chii-Min Hwu

School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan

Chii-Min Hwu & Wayne H. H. Sheu

Department of Environmental and Preventive Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan

Sahoko Ichihara

University of Chicago Research Bangladesh, Dhaka, Bangladesh

Md Tariqul Islam

Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland

Jost B. Jonas

Steno Diabetes Center Copenhagen, Gentofte, Denmark

Marit E. Jørgensen

National Institute of Public Health, Southern Denmark University, Copenhagen, Denmark

Marit E. Jørgensen

Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark

Torben Jørgensen & Allan Linneberg

Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Torben Jørgensen

Faculty of Medicine, Aalborg University, Aalborg, Denmark

Torben Jørgensen

Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, the University of Tokyo, Tokyo, Japan

Yoichiro Kamatani

Department of Clinical Diabetes, Endocrinology & Metabolism, Department of Translational Research and Cellular Therapeutics, City of Hope, Duarte, CA, USA

Fouad R. Kandeel

Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka

Anuradhani Kasturiratne & Ananda R. Wickremasinghe

Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Osaka, Japan

Tomohiro Katsuya

Department of Geriatric and General Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan

Tomohiro Katsuya

Division of General Internal Medicine and Geriatrics, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

Abel N. Kho

Center for Health Information Partnerships, Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

Abel N. Kho

Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore

Chiea-Chuen Khor & Jianjun Liu

Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, South Korea

Duk-Hwan Kim

Department of Regional Resource Management, Ehime University Faculty of Collaborative Regional Innovation, Ehime, Japan

Katsuhiko Kohara

Institute of Genetic Epidemiology, Department of Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, Austria

Florian Kronenberg & Sebastian Schönherr

Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland

Johanna Kuusisto, Alena Stančáková & Markku Laakso

Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia

Kristi Läll

Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA

Leslie A. Lange

Severance Biomedical Science Institute and Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea

Myung-Shik Lee

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea

Myung-Shik Lee

USC—Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, Philippines

Nanette R. Lee

Department of Medicine, Harvard Medical School, Boston, MA, USA

Aaron Leong, Miriam S. Udler, Jose C. Florez & James B. Meigs

Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA

Aaron Leong, Bianca Porneala & James B. Meigs

Department of Epidemiology and Biostatistics, Peking University Health Science Centre, Peking University, Beijing, China

Liming Li, Jun Lv & Canqing Yu

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands

Ruifang Li-Gao & Dennis O. Mook-Kanamori

Program in Medical & Population Genetics, Broad Institute, Cambridge, MA, USA

Cecilia M. Lindgren

Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK

Cecilia M. Lindgren

Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Allan Linneberg

Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore

Jianjun Liu, Rob M. van Dam & E-Shyong Tai

McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, USA

Adam E. Locke

Department of Medicine, Division of Genomics and Bioinformatics, Washington University School of Medicine, St Louis, MO, USA

Adam E. Locke

Department of Biostatistics and Data Science, University of Texas Health Science Center at Houston, Houston, TX, USA

Xi Luo

Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden

Valeriya Lyssenko & Leif Groop

Department of Clinical Science, Center for Diabetes Research, University of Bergen, Bergen, Norway

Valeriya Lyssenko

Dromokaiteio Psychiatric Hospital, National and Kapodistrian University of Athens, Athens, Greece

Vasiliki Mamakou

Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Thomas Meitinger

Institute of Human Genetics, Technical University of Munich, Munich, Germany

Thomas Meitinger

German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany

Thomas Meitinger & Annette Peters

The Usher Institute to the Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK

Andrew D. Morris

Digital Health Center, Digital Engineering Faculty of Hasso Plattner Institue and University Potsdam, Potsdam, Germany

Girish N. Nadkarni, Claudia Schurmann & Erwin P. Bottinger

The Division of Data Driven and Digital Medicine (D3M), Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Girish N. Nadkarni

Department of Medicine and Pharmacology, New York Medical College, Valhalla, NY, USA

Jerry L. Nadler

Data Tecnica International LLC, Glen Echo, MD, USA

Michael A. Nalls

Center for Alzheimer’s and Related Dementias, National Institutes of Health, Baltimore, MD, USA

Michael A. Nalls

William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK

Ioanna Ntalla

Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan

Yukinori Okada & Ken Suzuki

Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Osaka, Japan

Yukinori Okada

Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

Yukinori Okada

Instituto Nacional de Medicina Genómica, Mexico City, Mexico

Lorena Orozco

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA

Sanjay R. Patel

Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA

Mark A. Pereira & James S. Pankow

Department of Diabetes and Endocrinology, Nelson R. Mandela School of Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa

Fraser J. Pirie & Ayesha A. Motala

Academy of Scientific and Innovative Research, CSIR—Human Resource Development Centre Campus, Ghaziabad, India

Gauri Prasad & Dwaipayan Bharadwaj

Genomics and Molecular Medicine Unit, CSIR—Institute of Genomics and Integrative Biology, New Delhi, India

Gauri Prasad

Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

Laura J. Rasmussen-Torvik

Fred Hutchinson Cancer Research Center, Seattle, WA, USA

Alexander P. Reiner & Charles Kooperberg

Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke–NUS Medical School, Singapore, Singapore

Charumathi Sabanayagam, Tien-Yin Wong & Ching-Yu Cheng

Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore

Charumathi Sabanayagam, Tien-Yin Wong & Ching-Yu Cheng

Department of Pediatrics, Pediatric Diabetes Research Center, University of California San Diego, La Jolla, CA, USA

Maike Sander & Kyle J. Gaulton

Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA

Maike Sander & Kyle J. Gaulton

Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA

Maike Sander

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK

Naveed Sattar

Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Claudia Schurmann & Erwin P. Bottinger

Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA

Jennifer A. Smith

Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Konstantin Strauch

Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany

Konstantin Strauch

Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany

Konstantin Strauch

Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan

Ken Suzuki, Toshimasa Yamauchi & Takashi Kadowaki

Department of Genomic Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan

Atsushi Takahashi

Faculty of Medicine, University of Reykjavik, Reykjavik, Iceland

Unnur Thorsteinsdottir & Kari Stefansson

Faculty of Medicine, Macau University of Science and Technology, Macau, China

Brian Tomlinson

Department of Medical Genetics and Medical Research, China Medical University Hospital, Taichung, Taiwan

Fuu-Jen Tsai

Department of Health, Finnish Institute for Health and Welfare, Helsinki, Finland

Jaakko Tuomilehto

National School of Public Health, Madrid, Spain

Jaakko Tuomilehto

Department of Neuroscience and Preventive Medicine, Danube University Krems, Krems, Austria

Jaakko Tuomilehto

Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia

Jaakko Tuomilehto

Unidad de Biología Molecular y Medicina Genómica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

Teresa Tusie-Luna

Departamento de Medicina Genómica y Toxiología, Ambiental Instituto de Investigaciones Biomédicas, UNAM, Mexico City, Mexico

Teresa Tusie-Luna

Unidad de Investigacion Medica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico

Adan Valladares-Salgado & Miguel Cruz

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands

Jan B. van Klinken & Ko Willems van Dijk

Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands

Jan B. van Klinken & Ko Willems van Dijk

Department of Clinical Chemistry, Laboratory of Genetic Metabolic Disease, Amsterdam University Medical Center, Amsterdam, the Netherlands

Jan B. van Klinken

Southern California Eye Institute, CHA Hollywood Presbyterian Medical Center, Los Angeles, CA, USA

Rohit Varma

Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Marijana Vujkovic

Unidad de Investigación Médica en Epidemiologia Clinica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico

Niels Wacher-Rodarte

Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Eric A. Whitsel

Department of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands

Ko Willems van Dijk

Department of Public Health, Aarhus University, Aarhus, Denmark

Daniel R. Witte

Danish Diabetes Academy, Odense, Denmark

Daniel R. Witte

Diabetology Research Centre, King Edward Memorial Hospital and Research Centre, Pune, India

Chittaranjan S. Yajnik

Department of Medical Biochemistry, Kurume University School of Medicine, Kurume, Japan

Ken Yamamoto

Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia

Loïc Yengo

Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA

Jian-Min Yuan

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA

Jian-Min Yuan

Department of Pediatrics, Division of Genetic and Genomic Medicine, UCI Irvine School of Medicine, Irvine, CA, USA

Leslie J. Raffel

Department of Anti-Aging Medicine, Ehime University Graduate School of Medicine, Ehime, Japan

Michiya Igase

Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA

Susan Redline

Department of Medical Sciences, Uppsala University, Uppsala, Sweden

Lars Lind

Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA

Craig L. Hanis

Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA

Erik Ingelsson

Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden

Erik Ingelsson

Department of Epidemiology, University of Washington, Seattle, WA, USA

Bruce M. Psaty

Department of Health Services, University of Washington, Seattle, WA, USA

Bruce M. Psaty

Beijing Institute of Ophthalmology, Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Hospital, Capital Medical University, Beijing, China

Ya-Xing Wang

Department of Medicine, Division of Cardiology, Duke University School of Medicine, Durham, NC, USA

Yongmei Liu

Technical University of Munich (TUM) and Klinikum Rechts der Isar, TUM School of Medicine, Munich, Germany

Eleftheria Zeggini

Kurume University School of Medicine, Kurume, Japan

Mitsuhiro Yokota

Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA

Stephen S. Rich

Department of Medicine, McGill University, Montreal, Quebec, Canada

James C. Engert

Department of Human Genetics, McGill University, Montreal, Quebec, Canada

James C. Engert

Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, UK

Philippe Froguel

Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA

James G. Wilson

Division of Endocrinology and Metabolism, Department of Medicine, Taichung Veterans General Hospital, Taichung, Taiwan

M. Geoffrey Hayes & Wayne H. H. Sheu

Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

M. Geoffrey Hayes & M. Geoffrey Hayes

Department of Anthropology, Northwestern University, Evanston, IL, USA

M. Geoffrey Hayes

Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA

Francis S. Collins

Systems Genomics Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, India

Dwaipayan Bharadwaj

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada

Guillaume Paré

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea

Kyong-Soo Park

Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea

Kyong-Soo Park

Netherlands Heart Institute, Utrecht, the Netherlands

J. Wouter Jukema

MRC-PHE Centre for Environment and Health, Imperial College London, London, UK

Abbas Dehghan, Jaspal S. Kooner & John C. Chambers

Duke–NUS Medical School, Singapore, Singapore

E-Shyong Tai

Singapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore, Singapore

Woon-Puay Koh

Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

Woon-Puay Koh

Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, University of Dundee, Dundee, UK

Colin N. A. Palmer

Department of Medicine, Brown University Alpert School of Medicine, Providence, RI, USA

Simin Liu

Imperial College Healthcare NHS Trust, Imperial College London, London, UK

Jaspal S. Kooner & John C. Chambers

National Heart and Lung Institute, Imperial College London, London, UK

Jaspal S. Kooner

The Mindich Child Health and Development Institute, Ichan School of Medicine at Mount Sinai, New York, NY, USA

Ruth J. F. Loos

Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA

Danish Saleheen

Center for Non-Communicable Diseases, Karachi, Pakistan

Danish Saleheen

Computational Medicine, Berlin Institute of Health at Charité Universitätsmedizin, Berlin, Germany

Claudia Langenberg

Department of Advanced Genomic and Laboratory Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan

Shiro Maeda

Division of Clinical Laboratory and Blood Transfusion, University of the Ryukyus Hospital, Okinawa, Japan

Shiro Maeda

Department of Statistics, University of Oxford, Oxford, UK

Simon R. Myers

Section of Genetics and Genomics, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK

Jorge Ferrer

Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Anna L. Gloyn & Mark I. McCarthy

Division of Endocrinology, Department of Pediatrics, Stanford School of Medicine, Stanford University, Stanford, CA, USA

Anna L. Gloyn

Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA

Donald W. Bowden

Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, UK

Andrew P. Morris

NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester, UK

Andrew P. Morris