Four notable findings emerged in the present study: (1) the sensitivity for diabetes, dementia, and cancer being recorded as the underlying cause of death was poor but improved substantially if contributing causes of death were taken into account; (2) women with dementia who died before 2006 were less likely to […]
cohort
Effects of long-term antiretroviral therapy in reproductive-age women in sub-Saharan Africa (the PEPFAR PROMOTE study): a multi-country observational cohort study
Background We report the long-term impact of ART in women of reproductive age (15–49 years) in Africa who have been using ART for up to 10 years. We assess outcomes of retention, adherence, maternal health, fertility intentions, and safety. Methods This longitudinal, multicountry study (PROMOTE) enrolled women who initiated ART […]
Depression and cardiovascular disease are not linked by high blood pressure: findings from the SAPALDIA cohort
James, S. L. et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet 392, 1789–1858 (2018). Google Scholar Gan, Y. et al. Depression and […]
Data-driven subgroups of type 2 diabetes, metabolic response, and renal risk profile after bariatric surgery: a retrospective cohort study
Background A novel data-driven classification of type 2 diabetes has been proposed to personalise anti-diabetic treatment according to phenotype. One subgroup, severe insulin-resistant diabetes (SIRD), is characterised by mild hyperglycaemia but marked hyperinsulinaemia, and presents an increased risk of diabetic nephropathy. We hypothesised that patients with SIRD could particularly benefit […]