Metformin in Treatment-Resistant Bipolar Depression

Via Peters

Adjunctive metformin in bipolar disorder. Researchers performed a randomized clinical trial of treating insulin resistance to improve clinical outcomes in treatment-resistant bipolar depression. RESEARCH UPDATE Treatment-resistant bipolar depression (TRBD) is defined by non-remission after 2 8-week trials of recommended medications, including combination therapy, at therapeutic doses, and associated with increased […]

Anxiety and Depression in Kids: Ask the Expert

Via Peters

A child can develop anxiety or depression at any age, though they’re more likely to be diagnosed as they get older. According to the Centers for Disease Control and Prevention (CDC), from 2016 to 2019, 9.4 percent of children between the ages of 3 and 17 had an anxiety disorder, […]

Depression Symptoms Associated With Elevated Cardiovascular Risk

Via Peters

Study data published in the Journal of Psychosomatic Research identified an increased risk for cardiovascular disease in patients with depression. The association was most significant in patients with clinically relevant depressive symptoms. Patients with controlled depression did not have elevated cardiovascular risk compared with control participants. This retrospective study enrolled […]

Why Is There an Increase in Depression After COVID?

Via Peters

Are you one of the millions of people who contracted COVID? If so, you understand the physical symptoms that made you feel miserable for days or even weeks. However, you may have also felt fatigued, unmotivated, tearful, irritable, and sad even after the physical symptoms were gone. It’s true that […]

What is melancholic depression? Symptoms, diagnosis, and more

Via Peters

Most research sources list melancholia as a form of major depressive disorder, but there is still some controversy over this particular diagnosis. The scientific community does not agree on whether melancholic depression is a distinct type or subtype of depression or a severe symptom of this condition. This article discusses […]

Mother’s depression symptoms from preconception to postpartum linked with children’s behavioral issues

Via Peters

Children whose mothers experience rising levels of depression from the period before pregnancy until the months just after giving birth are at greater risk of developing emotional, social and academic problems during their youth, UCLA psychology researchers and colleagues report. Their recently published seven-year study, which tracked mothers and their […]

Geriatric depression: Symptoms, causes, treatments, more

Via Peters

Geriatric depression is a mental health condition affecting older adults. As with depression in younger adults, depression in older people can have many different causes and treatment options. Although geriatric depression is the most common of all mental health conditions in adults 65 years and older, health experts do not […]

AXS-05 Results in Reduction in Major Depression Symptoms

Via Peters

New data indicates a positive future for AXS-05 (dextromethorphan-bupropion) as a potential treatment for patients with major depressive disorder. The drug, developed by Axsome Therapeutics, is a novel, oral investigational N-methyl-D-aspartate (NMDA) receptor antagonist with multimodal activity. The results from the GEMINI phase 3 clinical trial show AXS-05 showed rapid, […]