Diabetes insipidus (DI) is a rare disease characterized by hypotonic urine output and polydipsia. We report the case of a 50-year-old male admitted for diabetic ketoacidosis (DKA) in an intensive care unit with sepsis and alcoholic pancreatitis who later developed DI. He had a high copeptin level of >21.4 pmol/L, […]
Diagnostic
A large trial of screening for gestational diabetes mellitus in the United States highlights the need to revisit the Australian diagnostic criteria
Recent trial results validate previous concerns about the IADPSG criteria for gestational diabetes The definition of gestational diabetes mellitus (GDM) varies considerably depending on the region where a woman lives, and considerable controversy remains on the best approach to diagnosis. A 2021 trial showed no benefit for women or infants […]
Yale Cancer Center Study Suggests Improved Diagnostic Testing Needed to Guide HER2 Breast Cancer Treatment
A new study by researchers at Yale Cancer Center shows using current standard human epidermal growth factor receptor 2 (HER2) assays as a diagnostic test may result in a mis-assignment of patients for treatment for breast cancer with a promising new drug. The study analyzed current assays used to determine […]