Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes

Via Peters

Generation, genetics, and immunological phenotypes of B6 RIP-DTR mice RIP-DTR mouse strains were initially generated and maintained on mixed B6/CBA genetic backgrounds for studies of beta cell regeneration7,10,11. To make an inbred strain of RIP-DTR mice for transplantation studies, we repeatedly backcrossed to B6.SJL-Ptprca Pepcb/BoyJ mice, commonly referred to as […]