Primary radiotherapy and deep inferior epigastric perforator flap reconstruction for patients with breast cancer (PRADA): a multicentre, prospective, non-randomised, feasibility study

Via Peters

Introduction A longstanding challenge in oncoplastic breast surgery is the optimal integration of breast reconstruction and post-mastectomy radiotherapy, which is compounded by broadening indications for post-mastectomy radiotherapy. Patients increasingly choose immediate breast reconstruction, but post-mastectomy radiotherapy is associated with complications. Compared with non-irradiated implants, irradiated implants have been shown to […]

Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients

Via Peters

Summary Background Previous studies have independently validated the prognostic relevance of residual cancer burden (RCB) after neoadjuvant chemotherapy. We used results from several independent cohorts in a pooled patient-level analysis to evaluate the relationship of RCB with long-term prognosis across different phenotypic subtypes of breast cancer, to assess generalisability in […]