Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Via Peters

In a recent study published on the bioRxiv* preprint server, researchers demonstrate that avasimibe (AVS)-mediated inhibition of Acyl-CoA: cholesterol acyltransferase (ACAT) blocks the entry and fusion of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in different cell types. Study: An ACAT inhibitor regulates SARS-CoV-2 replication and antiviral T cell activity. […]